Description

Pharmacogenomic (PgX) Test

Understand How Your Genes Influence Your Response to 140+ Medications

At-home buccal swab | Shipped nationwide |

What Is the PgX Test?

The Pharmacogenomic (PgX) Test analyzes how your genetic makeup affects your body’s ability to absorb, metabolize, and respond to medications. Rather than using a trial-and-error approach, this test provides precision-based, DNA-guided treatment decisions, allowing your healthcare provider to select the most effective medication and dosage for your unique genetic profile.

Whether you're dealing with medication side effects, trying a new prescription, or managing multiple drugs, this test offers clear answers.

How It Works

  • Simple, at-home cheek swab
  • No needles, no lab visit
  • Ships nationwide
  • Results in approximately 10–14 business days

Who Should Consider This Test?

  • Individuals who have experienced side effects from medications
  • Patients who feel like a medication “just doesn’t work”
  • Those taking multiple prescriptions (polypharmacy)
  • People with chronic conditions starting long-term drug therapy
  • Mental health patients trying or switching medications
  • Anyone who wants a personalized approach to health care

What the Test Evaluates

The PgX test analyzes over 40 key genes involved in drug metabolism and medication response. These include:

  • CYP450 family: CYP2D6, CYP2C19, CYP3A4, CYP2C9
  • Other pharmacogenes: SLCO1B1, VKORC1, COMT, MAOA, HLA-B, UGT1A1, and more

Your results will categorize how your body metabolizes medications:

  • Poor Metabolizer
  • Intermediate Metabolizer
  • Normal (Extensive) Metabolizer
  • Ultra-Rapid Metabolizer

This information helps healthcare providers adjust dosages, avoid side effects, or recommend safer alternatives.

Medications Covered

The PgX test assesses response to over 140 prescription medications across many categories:

Mental Health

  • Antidepressants: Citalopram, Fluoxetine, Sertraline, Duloxetine, Bupropion
  • Antipsychotics: Risperidone, Olanzapine, Quetiapine, Clozapine
  • Anti-Anxiety: Diazepam, Lorazepam, Alprazolam
  • ADHD: Atomoxetine, Methylphenidate, Amphetamine

Cardiovascular

  • Blood Thinners: Warfarin, Clopidogrel
  • Statins: Simvastatin, Atorvastatin
  • Beta Blockers: Metoprolol, Carvedilol
  • ACE Inhibitors/ARBs: Lisinopril, Losartan

Pain Management

  • Opioids: Codeine, Tramadol, Hydrocodone
  • NSAIDs: Ibuprofen, Naproxen, Celecoxib

Digestive Health

  • PPIs: Omeprazole, Pantoprazole
  • Antiemetics: Ondansetron, Metoclopramide

Diabetes

  • Glucose Meds: Metformin, Glimepiride, Repaglinide

Immunology & Autoimmune

  • Immunosuppressants: Azathioprine, Tacrolimus
  • Other: Abacavir (HIV), Allopurinol (Gout)

Women’s Health & Hormones

  • Ethinyl Estradiol, Drospirenone, Estradiol

Other Medications

  • Sumatriptan (Migraines), Tamoxifen (Breast Cancer)
  • Theophylline (Asthma), Mirabegron (Bladder)
  • Eliglustat (Lysosomal Storage Disorders)

What You’ll Receive

  • A comprehensive genetic report highlighting how your DNA affects drug metabolism
  • Medication-specific insights such as:
  • “Use with caution”
  • “Consider lower/higher dose”
  • “Try alternative medication”
  • Guidance your provider can use to optimize your treatment plan based on science, not guesswork

Why It Matters

Your genes don’t change—but your prescriptions might. This one-time test offers lifelong insight into how your body handles medications, making every future prescription decision safer and smarter.