Description

The MMR IgG panel measures immunoglobulin G (IgG) antibodies in your blood against measles, mumps, and rubella viruses. This test determines whether a person has immunity to these infections, either from previous vaccination or past infection.

Purpose of the Test

  • Assess immunity: Confirms if you are protected against measles, mumps, and rubella.
  • Pre-vaccination screening: Determines if a booster dose of the MMR vaccine is needed.
  • Post-exposure assessment: Helps identify whether an individual is at risk after contact with someone who has MMR.
  • Prenatal screening: Ensures immunity in women before or during pregnancy to prevent congenital rubella syndrome.

Clinical Significance

  • Measles: Highly contagious viral infection causing fever, cough, runny nose, rash, and in severe cases, pneumonia or encephalitis.
  • Mumps: Viral infection causing fever, headache, and painful swelling of the salivary glands; can lead to complications like orchitis or meningitis.
  • Rubella: Mild viral infection in children and adults, but can cause severe birth defects if a pregnant woman is infected.

Test Details

  • Sample: Blood
  • Preparation: Fasting not required
  • Interpretation:
  • Positive IgG: Indicates immunity to the virus.
  • Negative IgG: Suggests susceptibility, and vaccination may be recommended.

This panel is commonly ordered for school entry, healthcare workers, travelers, or women planning pregnancy to ensure protection against these preventable viral infections.