Description
Immunoglobulin M (IgM) anti-myelin associated glycoprotein (MAG) antibodies are autoantibodies that can indicate autoimmune demyelinating neuropathies. The presence of these antibodies suggests that the body's immune system is attacking cells that maintain a healthy peripheral nervous system.
What causes anti-MAG antibodies?
- In about 98% of cases, anti-MAG antibodies are caused by monoclonal gammopathy, an abnormal increase in the number of antibody-producing cells.
- Monoclonal gammopathy of undetermined significance (MGUS) is a condition that can be associated with anti-MAG neuropathy. MGUS is a potentially cancerous condition that involves an overproduction of serum immunoglobulins.
What are the symptoms of anti-MAG neuropathy?
- Anti-MAG neuropathy can cause sensory and motor problems.
- Symptoms include numbness, burning, tingling, and sensitivity to touch or temperature.
- Symptoms are often worse at night.
Fasting not required.
