Description
The C-terminal telopeptide (CTX) test measures the level of degraded bone fragments in your bloodstream. CTX is a breakdown product of type 1 collagen and serves as a biomarker of bone resorption and turnover.
Why the CTX Test Is Important
- Osteoporosis Detection and Monitoring: Elevated CTX levels indicate increased bone turnover, which can signal osteoporosis or heightened risk of fractures.
- Monitoring Bone Health: CTX testing can track bone loss in conditions such as:
- Osteopenia
- Paget’s disease of the bone
- Hyperthyroidism or hypothyroidism affecting bone metabolism
By measuring CTX levels, healthcare providers can evaluate bone health, monitor treatment effectiveness, and guide strategies to reduce bone loss.
Fasting: Not required.

