Description

Crohn’s disease is a chronic inflammatory bowel disease (IBD) that causes long-term inflammation in the digestive tract. While its exact cause is unknown, it's believed to involve an abnormal immune response, environmental triggers, and possible microbial or genetic influences. This panel helps assess inflammation, immune response, and potential infectious triggers commonly evaluated during diagnosis or management of Crohn’s disease.

Common Symptoms of Crohn’s Disease:

  • Chronic diarrhea
  • Abdominal pain and cramping
  • Unexplained weight loss
  • Anemia and fatigue
  • Fever
  • Mouth sores
  • Bloody stool
  • Reduced appetite

Symptoms may develop gradually or appear suddenly, and may fluctuate between flare-ups and remission.

This Panel Includes the Following Biomarkers:

Anti-Saccharomyces Cerevisiae Antibodies (ASCA) IgG and IgA

  • Purpose: Detects antibodies against Saccharomyces cerevisiae, a yeast commonly found in the gut.
  • Why it matters: Elevated ASCA levels are frequently seen in Crohn’s disease and can help distinguish it from other inflammatory bowel conditions, such as ulcerative colitis.

C-Reactive Protein (CRP)

  • Purpose: Measures inflammation levels throughout the body.
  • Why it matters: CRP is often elevated during Crohn’s flares, and can help track disease activity and treatment effectiveness.

Comprehensive Metabolic Panel (CMP) with eGFR

  • Purpose: Evaluates kidney and liver function, electrolytes, and glucose levels.
  • Why it matters: Chronic inflammation and certain Crohn’s medications can impact organ function and electrolyte balance. This panel helps monitor overall systemic health.

Complete Blood Count (CBC)

  • Purpose: Assesses red and white blood cells and platelet levels.
  • Why it matters: Identifies anemia, infection, or inflammation—common issues in Crohn’s patients due to blood loss, malabsorption, or immune activity.

Test Preparation:

  • Fasting: Not required
  • Sample Type: Blood (venipuncture)

Who Should Consider This Panel:

  • Individuals with chronic gastrointestinal symptoms (diarrhea, abdominal pain, weight loss)
  • Patients with a suspected diagnosis of Crohn’s disease or IBD
  • Those experiencing flares or changes in symptoms
  • Individuals monitoring treatment response or complications
  • Providers seeking a non-invasive tool to support IBD diagnosis

Why This Panel Matters:

There is no single test for Crohn’s disease, but this targeted blood panel offers key diagnostic biomarkers to help identify patterns of inflammation, immune activation, and systemic effects that are characteristic of Crohn’s. It supports early detection and guides clinical decision-making—empowering patients and providers alike in managing this complex condition.

Take control of your digestive health with answers that matter.

This panel is a valuable first step toward a comprehensive diagnosis and more effective care.