Description

The Fibrosis-4 (FIB-4) test is a noninvasive blood test that estimates the potential for scarring in the liver. It's used to screen for advanced liver fibrosis, such as cirrhosis. 

How it works

  • The FIB-4 test measures a patient's age, aspartate aminotransferase (AST) level, alanine aminotransferase (ALT) level, and platelet count. 
  • A formula is used to calculate the FIB-4 score. 
  • The FIB-4 score is categorized as low (<1.30), indeterminate (1.30–2.67), or high (>2.67). 

What it can help identify

  • The FIB-4 test can help identify patients with severe fibrosis or cirrhosis. 
  • It can help identify patients who might be able to avoid a liver biopsy. 

Fasting not required.