Description

Supporting the Evaluation and Monitoring of Bipolar Disorder

Manic depression—now more commonly referred to as bipolar disorder—is a mental health condition marked by extreme mood swings, ranging from manic (high energy or irritability) to depressive (low energy or sadness) episodes. While bipolar disorder is primarily diagnosed based on symptoms and clinical history, lab testing can support diagnosis, rule out medical contributors, and monitor medication safety.

This panel is designed to support both initial assessment and ongoing management of individuals with bipolar disorder or related symptoms.

This Panel Includes:

  • Comprehensive Metabolic Panel (CMP)
  • Lithium Level (if patient is taking lithium medication)
  • Thyroid Stimulating Hormone (TSH)

Fasting is not required for this panel.

Why These Tests Are Included

Comprehensive Metabolic Panel (CMP):

Evaluates liver and kidney function, electrolytes, and glucose levels.

  • Useful in identifying underlying medical conditions that can mimic or worsen bipolar symptoms.
  • Important for monitoring organ function in individuals taking psychiatric medications, especially mood stabilizers.

Lithium Level:

Monitors the blood concentration of lithium, a common mood stabilizer used in bipolar disorder.

  • Ensures levels remain in the therapeutic range—too low may be ineffective, too high can be toxic.
  • Regular monitoring is essential for safety and medication effectiveness.

Thyroid Stimulating Hormone (TSH):

Screens for thyroid dysfunction.

  • Both hypothyroidism and hyperthyroidism can cause mood changes and mimic bipolar symptoms.
  • Thyroid dysfunction is also a known side effect of certain mood stabilizing medications, including lithium.

What Are the Symptoms of Bipolar Disorder?

  • Manic episodes:
  • Elevated or irritable mood, rapid speech, racing thoughts, decreased need for sleep, risky behavior
  • Depressive episodes:
  • Low mood, loss of interest, fatigue, feelings of worthlessness, thoughts of death or suicide
  • Other signs:
  • Difficulty concentrating or making decisions
  • Changes in behavior or sleep patterns
  • Sudden mood or energy shifts without clear cause

Who Should Consider This Panel?

  • Individuals experiencing extreme or unexplained mood swings
  • Those currently taking or being considered for lithium therapy
  • Providers monitoring patients on bipolar medications
  • Anyone wanting to rule out medical contributors to mood instability

Why Lab Testing Is Important

Blood work helps ensure that underlying medical issues are not being overlooked, and that medications used to treat bipolar disorder are being managed safely. In many cases, these lab tests help create a clearer clinical picture and support more effective treatment.