Description
A Comprehensive Look at Your Nutritional & Metabolic Health
Are you taking supplements—but wondering what your body may actually need?
Metabolomix+® from Genova Diagnostics is a comprehensive functional nutritional assessment designed to identify patterns that may indicate increased needs for specific nutrients and metabolic support.
Using primarily a first-morning urine sample, Metabolomix+ examines nutritional and metabolic biomarkers associated with vitamins, amino acids, energy production, oxidative stress, methylation, detoxification and other important biochemical pathways.
What Does Metabolomix+ Evaluate?
B-Vitamin Needs
Metabolomix+ evaluates metabolic markers that may suggest functional needs for important B vitamins, including pathways associated with:
- Vitamin B1
- Vitamin B2
- Vitamin B3
- Vitamin B6
- Folate
- Vitamin B12
- Biotin
Instead of simply measuring how much of a vitamin is circulating in the bloodstream, functional nutritional testing examines metabolites produced during biochemical reactions.
Mitochondrial Function & Energy Production
Your mitochondria help convert nutrients into cellular energy.
Metabolomix+ evaluates multiple organic acids involved in energy-production pathways, including markers related to the Krebs/citric-acid cycle.
These results may provide insight into areas where nutritional support could be considered.
Amino Acids
The test evaluates a broad range of amino acids and related metabolites.
Amino acids are important for:
- Muscle and tissue repair
- Neurotransmitter production
- Detoxification
- Immune function
- Antioxidant production
- Energy metabolism
Oxidative Stress & Antioxidant Support
Metabolomix+ evaluates biomarkers associated with oxidative stress and antioxidant requirements.
This includes 8-OHdG, a marker associated with oxidative damage to DNA.
The report integrates multiple findings to help identify whether additional antioxidant support may be appropriate.
Methylation
Methylation is involved in numerous biological processes, including:
- DNA regulation
- Neurotransmitter metabolism
- Homocysteine metabolism
- Detoxification
- Cellular repair
Metabolomix+ evaluates several metabolic markers associated with methylation pathways, including methylmalonic acid, methionine, FIGLU, sarcosine, glycine and serine.
Detoxification & Toxic Exposure
The profile includes biomarkers that may provide information about toxic exposure and the body's biochemical response to environmental compounds.
Additional toxic-element testing may also be available.
Digestive & Microbial Metabolites
Certain urinary organic acids can provide clues about metabolites produced by intestinal microorganisms and digestive processes.
These findings can add another piece to the overall nutritional and metabolic picture.
Personalized Nutritional Recommendations
One of the advantages of Metabolomix+ is that the report doesn't simply provide a long list of laboratory values.
Genova organizes the results into biochemical pathways and provides nutritional recommendations based on the patient's findings.
Recommendations may address:
Antioxidants B Vitamins Minerals Amino Acids Essential Fatty Acids Digestive Support
This can help make nutritional supplementation more targeted rather than simply guessing which supplements may be needed.
Who May Benefit From Metabolomix+?
This testing may be worth considering for individuals dealing with or interested in:
- Fatigue or low energy
- Chronic stress
- Nutritional concerns
- Restricted or unusual diets
- Mitochondrial function
- Oxidative stress
- Inflammation
- Methylation
- Healthy aging
- Personalized supplementation
- General health optimization
It may also be useful for someone already taking numerous supplements who wants additional information to help determine where nutritional support may be most appropriate.
Convenient At-Home Collection
One of the biggest advantages of Metabolomix+ is that the core test does not require a traditional blood draw.
The primary specimen is a first-morning void (FMV) urine sample collected at home.
We Can Ship the Test Kit Directly to You
You don't have to live near Labs By Request to order Metabolomix+.
Your Genova Diagnostics collection kit can be shipped directly to your home.

