Description

Methylation Panel – A Comprehensive Insight into Your Biochemistry

Methylation is a core biochemical process essential for regulating everything from gene expression to detoxification and mood. Our Methylation Panel offers an in-depth assessment of your body’s methylation efficiency by analyzing critical metabolites and key genetic variants (SNPs) that influence this pathway.

This comprehensive panel helps uncover hidden imbalances that may be affecting your energy, mental clarity, immune function, or risk of chronic disease.

What is Methylation?

Methylation is the transfer of methyl groups (CH₃) between molecules—a process that happens billions of times per second in the body. These methyl groups function like molecular "switches," turning genes on or off and supporting a wide range of physiological functions, including:

  • DNA and RNA synthesis
  • Neurotransmitter production
  • Detoxification and hormone metabolism
  • Immune system balance
  • Cellular energy production
  • Healthy aging and repair mechanisms

Methylation efficiency is influenced by both nutrition (e.g., B-vitamins, amino acids, minerals) and genetics. Impairments can disrupt your body’s ability to function optimally.

Why Methylation Matters

Dysregulated methylation has been associated with a variety of health concerns, including:

  • Cardiovascular disease
  • Cancer risk
  • Mood and psychiatric disorders
  • Neurodegenerative conditions
  • Fatigue and poor detoxification
  • Hormone imbalance and infertility

Who Should Consider This Test?

The Methylation Panel is especially valuable for individuals with:

  • Chronic fatigue or low energy
  • Cognitive decline or memory issues
  • Depression, anxiety, or mood disorders
  • Detoxification concerns or high toxin exposure
  • Family history of cardiovascular disease or cancer
  • Neurological conditions such as Parkinson’s or MS
  • Hormonal imbalances or infertility
  • Long-standing chronic illness with unclear cause

What’s Included in the Methylation Panel

This panel evaluates biomarkers and genetic variations involved in the methylation cycle:

Biochemical Markers (Plasma):

  • Methionine
  • Homocysteine
  • SAMe (S-adenosylmethionine)
  • SAH (S-adenosylhomocysteine)
  • SAMe/SAH Ratio
  • Methylation Balance Ratio
  • Betaine
  • Choline
  • Betaine/Choline Ratio
  • Dimethylglycine (DMG)
  • Cystathionine
  • Cysteine
  • Glutathione
  • Glycine
  • Sarcosine
  • Serine
  • Taurine
  • Met/Sulf Ratio

Genetic Analysis (Buccal Swab):

  • Key single nucleotide polymorphisms (SNPs) related to methylation efficiency (e.g., MTHFR, MTR, CBS, COMT)

Preparation & Sample Collection

  • Fasting Required: Please fast for 8–12 hours before testing for the most accurate biochemical readings.
  • Samples Collected:
  • Plasma (blood draw) for methylation metabolites
  • Buccal swab for SNP/genetic analysis

How the Results Help

The insights from this test can guide your provider in:

  • Identifying nutritional deficiencies impacting methylation
  • Recommending targeted supplementation (e.g., B12, folate, SAMe, or antioxidants)
  • Personalizing treatment plans based on your genetic predisposition
  • Supporting detoxification, mental health, immune resilience, and energy levels

Take the First Step Toward Biochemical Balance

Methylation affects nearly every system in your body. If you’re dealing with unexplained symptoms or want to proactively support your long-term health, the Methylation Panel provides the data you need to make informed, targeted decisions.

Order your Methylation Panel today and uncover the biochemical imbalances that may be impacting your well-being.