Description

The Risk of Ovarian Malignancy Algorithm (ROMA) is a test that helps determine the likelihood of ovarian cancer in women with an ovarian mass. ROMA is a logistic regression model that combines serum levels of two biomarkers, menopausal status, and other factors to calculate a numerical score. 

What it does 

  • Helps determine if an ovarian mass is benign or malignant
  • Helps identify women who are at high or low risk for ovarian cancer
  • Helps triage patients to gynecologic oncologists

How it works 

  • Analyzes serum levels of the biomarkers human epididymis protein 4 (HE4) and cancer antigen 125 (CA125)
  • Considers menopausal status
  • Calculates a numerical score

Fasting not required.