Description
The Prealbumin Blood Test measures levels of prealbumin (transthyretin), a protein produced by the liver that plays a key role in transporting thyroxine (T4) and retinol-binding protein (vitamin A). Because prealbumin has a short half-life of 2–3 days, it is a highly sensitive marker for recent changes in protein status and nutritional intake.
This test is often used to evaluate malnutrition, monitor recovery in hospitalized patients, and assess the effectiveness of nutrition therapy.
What This Test Measures
- Prealbumin (Transthyretin):
- Reflects current protein stores and nutritional status more quickly than albumin.
- Clinical Significance:
- Low prealbumin: May indicate malnutrition, protein deficiency, liver disease, or inflammatory states.
- High prealbumin: Can be seen with kidney disease or corticosteroid use.
Why This Test May Be Ordered
- To assess nutritional status in patients with weight loss, poor intake, or chronic illness
- To monitor protein nutrition in hospitalized or critically ill patients
- To evaluate the effectiveness of nutritional supplementation or therapy
- To help detect early protein deficiency before albumin levels are affected
Key Benefits of Prealbumin Testing
- Provides rapid insight into protein and nutrition status
- Helps guide dietary interventions or supplementation
- Supports early detection of malnutrition
- Can be used with albumin and total protein tests for a comprehensive evaluation
Test Details
- Sample Type: Blood draw
- Fasting Required: No
