Description
The Serum Protein Electrophoresis (SPEP) Blood Test separates and measures the different proteins in the blood, including albumin and globulins. This test helps evaluate immune system function, nutritional status, and chronic disease presence.
SPEP is often used to detect abnormal protein patterns, such as monoclonal proteins, which can indicate conditions like multiple myeloma, chronic infections, liver disease, or autoimmune disorders.
Purpose of the Test
- Identify abnormal protein levels or patterns
- Detect monoclonal gammopathies (e.g., multiple myeloma)
- Assess nutritional status and liver function
- Monitor chronic infections or inflammatory conditions
- Evaluate immune system health and antibody production
Who Should Consider This Test?
- Individuals with unexplained fatigue, weakness, or weight loss
- Patients with suspected multiple myeloma or other plasma cell disorders
- People with chronic infections or autoimmune disorders
- Individuals with liver or kidney disease
- Patients undergoing evaluation for abnormal blood protein levels
What the Test Measures
- Albumin: The main protein in blood, reflecting nutritional status and liver function
- Globulins (Alpha, Beta, Gamma): Proteins involved in immune response and inflammation
- Monoclonal Proteins (M-Proteins): Abnormal proteins that may indicate plasma cell disorders
Abnormal protein patterns may suggest immune disorders, chronic disease, or protein metabolism issues.
Fasting Required?
No fasting required.
