Description

The Sjogren's Anti-SS-A (Ro) and Anti-SS-B (La) Blood Test measures specific autoantibodies associated with Sjogren’s syndrome, an autoimmune disorder that primarily affects the glands producing saliva and tears.

This test helps healthcare providers confirm a diagnosis, monitor disease activity, and guide treatment for patients experiencing dry eyes, dry mouth, and other autoimmune symptoms.

Purpose of the Test

  • Detect autoantibodies associated with Sjogren’s syndrome
  • Support diagnosis of primary or secondary Sjogren’s syndrome
  • Assess risk for systemic autoimmune complications
  • Guide treatment planning and monitor response to therapy
  • Differentiate Sjogren’s syndrome from other autoimmune disorders

Who Should Consider This Test?

  • Individuals experiencing dry eyes, dry mouth, or chronic fatigue
  • Patients with joint pain, inflammation, or systemic autoimmune symptoms
  • People with family history of autoimmune disease
  • Individuals being evaluated for rheumatologic conditions
  • Patients already diagnosed with autoimmune disorders seeking monitoring

What the Test Measures

  • Anti-SS-A (Ro) Antibodies: Autoantibodies often present in Sjogren’s syndrome and sometimes lupus; associated with systemic involvement.
  • Anti-SS-B (La) Antibodies: Autoantibodies more specific to Sjogren’s syndrome; help confirm diagnosis.

Positive results indicate the presence of autoantibodies, supporting the diagnosis of Sjogren’s syndrome or related autoimmune conditions.

Negative results do not rule out the disease entirely but may prompt additional testing.

Fasting Required?

No fasting required.