Description
This test measures TPO antibodies, which are proteins produced by the immune system when it attacks the thyroid gland. TPO is an enzyme crucial for producing thyroid hormones that regulate your metabolism, energy, and growth.
When thyroid cells are damaged, TPO can leak into the bloodstream—triggering the production of these antibodies. High levels may indicate an autoimmune thyroid condition.
Why It's Important:
- Helps identify Hashimoto’s thyroiditis, the most common cause of hypothyroidism
- May be recommended if your TSH is elevated, or if you’re pregnant and at risk for thyroid problems
- A positive result usually confirms an autoimmune cause of thyroid dysfunction
- A negative result may point to other causes, such as infections or medication side effects
Fasting not required.
This test helps uncover the underlying cause of thyroid issues—especially when hormone levels alone don’t explain symptoms.