Description
This panel is designed to evaluate nerve function and potential neuropathies by measuring biomarkers associated with nerve damage, vitamin deficiencies, and metabolic issues that affect the nervous system. Reflex testing means that if an initial abnormal result is detected, additional confirmatory or specific tests are automatically performed to pinpoint the cause.
Purpose of the Test
- Diagnose neuropathies: Identifies sensory, motor, or autonomic nerve dysfunction.
- Assess severity and progression: Helps clinicians understand the extent of nerve damage.
- Detect underlying causes: Can reveal vitamin deficiencies, metabolic imbalances, or autoimmune contributions to nerve injury.
- Guide treatment: Helps determine which interventions—such as nutritional supplementation or medication—may be effective.
What the Test Measures
- Vitamin B12 and B1 (Thiamine): Essential for nerve health; deficiencies can cause neuropathy.
- Folate: Deficiency can contribute to nerve dysfunction.
- Homocysteine: Elevated levels may indicate B-vitamin deficiencies affecting nerves.
- Methylmalonic Acid (MMA): Elevated in B12 deficiency and associated nerve injury.
- Other neuropathy markers: Depending on the lab, this may include antibodies, metabolic markers, or toxins that impact nerve function.
Symptoms Suggesting Testing
- Numbness or tingling in hands or feet
- Burning or stabbing pain in extremities
- Muscle weakness or cramping
- Balance or coordination difficulties
- Reduced reflexes or abnormal sensory responses
Test Details
- Sample: Blood
- Preparation: Fasting not required
- Reflex Testing: Abnormal results trigger further testing automatically to clarify the cause of neuropathy.
This panel is especially useful for patients with diabetes, autoimmune conditions, nutritional deficiencies, or unexplained nerve symptoms, allowing early detection and targeted management of neuropathic conditions.
