Description

Andropause, sometimes referred to as "male menopause," is a condition linked to the gradual decline of testosterone and other hormone levels in men, typically beginning in their 40s or 50s. Unlike menopause in women, which occurs rapidly and universally, andropause develops slowly and variably, with some men experiencing more significant symptoms than others.

This panel evaluates key hormonal biomarkers to assess androgen status and identify potential causes of hormonal imbalance contributing to symptoms.

Common Symptoms of Andropause

  • Low energy and persistent fatigue
  • Decreased sex drive (low libido)
  • Erectile dysfunction
  • Mood changes: irritability, anxiety, or depression
  • Loss of muscle mass and strength
  • Increased abdominal or body fat
  • Difficulty with concentration or memory

Included Biomarkers

1. Testosterone (Bioavailable) with Sex Hormone Binding Globulin (SHBG)

  • Testosterone BIO: Measures the bioavailable (active) portion of testosterone that is free or loosely bound to albumin and available to tissues.
  • SHBG: A protein that binds tightly to testosterone, affecting how much is freely available.
  • Clinical relevance: Low bioavailable testosterone levels may explain symptoms like reduced libido, fatigue, and muscle loss, even when total testosterone is within normal range.

2. Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH)

  • LH: Stimulates testosterone production in the testes.
  • FSH: Involved in sperm production.
  • Clinical relevance: These pituitary hormones help determine whether low testosterone is due to primary testicular dysfunction or secondary causes (e.g., pituitary or hypothalamic issues).

3. Dehydroepiandrosterone Sulfate (DHEA-S)

  • A precursor hormone produced by the adrenal glands, involved in the synthesis of androgens and estrogens.
  • Clinical relevance: Low DHEA-S levels may be associated with fatigue, low libido, reduced muscle mass, and age-related hormonal decline.

Fasting Requirements:

  • Fasting: Not required for this panel.

Purpose of the Panel:

This blood panel helps:

  • Evaluate hormonal causes of symptoms related to andropause
  • Differentiate between primary and secondary hypogonadism
  • Guide decisions on hormone replacement therapy (HRT) or other interventions
  • Monitor age-related hormonal decline in men

The Andropause Blood Panel is a focused diagnostic tool for men experiencing symptoms of hormonal imbalance. By evaluating testosterone and related hormones, it offers valuable insight into male aging and supports personalized treatment planning.