Description

The Functional Health Panel (Male) is an advanced, full-spectrum lab testing package used in functional and integrative medicine to evaluate the physiological performance of multiple organ systems — not merely to detect disease, but to understand the underlying imbalances that lead to poor health.

This panel is designed for men of all ages, particularly those who are:

  • Proactive about preventive health and longevity
  • Managing chronic symptoms without a clear diagnosis
  • Focused on athletic performance, biohacking, or optimal aging
  • Seeking personalized interventions based on deep biomarker insight

Biomarker Categories & Clinical Relevance

Hormonal & Endocrine Function

These biomarkers evaluate the body’s hormone production, regulation, and balance — essential for energy, libido, mood, metabolism, and muscle mass.

  • Testosterone (Total & Free) – Assesses androgen status; low levels may result in fatigue, low libido, muscle loss, or depression.
  • Sex Hormone Binding Globulin (SHBG) – Affects testosterone availability; high SHBG can reduce free testosterone.
  • Free PSA & % Free PSA – Screens for prostate health and distinguishes between benign and malignant causes of elevated PSA.
  • Luteinizing Hormone (LH) & Follicle Stimulating Hormone (FSH) – Evaluate pituitary function and regulation of testosterone and sperm production.
  • Estradiol (E2) – Essential in men for bone health, libido, and fat regulation; imbalance can cause gynecomastia or mood changes.
  • Prolactin – Elevated levels may inhibit testosterone and signal pituitary dysfunction.
  • Cortisol (AM) – A key stress hormone; high or low levels indicate adrenal dysregulation or HPA axis fatigue.
  • Dehydroepiandrosterone Sulfate (DHEA-S) – A precursor to sex hormones; low levels may correlate with aging, stress, and poor resilience.

Thyroid Health

Thyroid function influences metabolism, energy, mood, and weight regulation.

  • TSH (Thyroid Stimulating Hormone) – Primary screening tool for thyroid function.
  • Free T3 (fT3) & Free T4 (fT4) – Measure active thyroid hormones. Low levels can result in fatigue, cold intolerance, or depression.
  • Anti-TPO & Anti-Tg – Detect autoimmune thyroid disease (e.g., Hashimoto’s or Graves’).

Advanced Cardiovascular & Lipid Profile

Goes beyond basic cholesterol testing to assess atherogenic risk, inflammation, and particle size.

  • Apo B – Measures atherogenic particles; superior to LDL-C in predicting cardiovascular risk.
  • Lipoprotein(a) [Lp(a)] – A genetic risk factor for heart disease not affected by diet or exercise.
  • LDL-P, LDL Size – Particle number and size indicate plaque-forming potential.
  • HDL-P, HDL Size – Assess the number and quality of protective HDL particles.
  • Large HDL-P, Large VLDL-P, Small LDL-P – Detail lipoprotein subclass profile.
  • LP-IR Score – An insulin resistance score based on lipid particle data.
  • Homocysteine – Elevated levels may contribute to arterial damage and stroke risk.
  • High-Sensitivity CRP (hs-CRP) – A sensitive marker of systemic inflammation and cardiovascular risk.
  • Ferritin – Reflects iron storage and is also an acute-phase reactant in inflammation.

Essential Fatty Acid & Omega Profile

Evaluates the balance of pro-inflammatory and anti-inflammatory fatty acids for cellular health and inflammation control.

  • EPA, DHA, DPA – Omega-3 fatty acids with anti-inflammatory and cardiovascular benefits.
  • AA (Arachidonic Acid), LA (Linoleic Acid) – Omega-6 fatty acids; excessive levels may contribute to chronic inflammation.
  • Total Omega-3 & Omega-6 – Overall balance affects cardiovascular, cognitive, and immune health.
  • AA/EPA Ratio – A key indicator of inflammatory status.
  • Omega-6/Omega-3 Ratio – Optimal balance supports cellular function and reduces chronic disease risk.
  • EPA+DPA+DHA – Combined Omega-3 index used in cardiometabolic assessment.

Nutrient & Mineral Status

Identifies common nutritional imbalances that affect metabolism, energy, immune function, and detoxification.

  • Vitamin D (25-OH) – Essential for immune health, bone strength, and hormone production.
  • Zinc – Supports immune function, testosterone production, and wound healing.
  • Magnesium – Vital for muscle contraction, nerve conduction, and energy metabolism.
  • MMA (Methylmalonic Acid) – Functional marker for Vitamin B12 deficiency.
  • Iron, TIBC, UIBC, Transferrin Saturation – Complete iron panel to assess for deficiency or overload.
  • Uric Acid – Marker for gout risk and metabolic health.

Liver, Kidney & Digestive Function

Assesses detoxification capacity and organ health under physical, environmental, or metabolic stress.

  • GGT, ALT, AST, ALP, Bilirubin – Liver enzymes to detect liver stress, NAFLD, or damage.
  • Amylase, Lipase – Pancreatic enzymes relevant to digestion and pancreatic function.
  • Microalbumin, Creatinine, Microalbumin/Creatinine Ratio – Detect early kidney damage or vascular issues.

🔹 Autoimmune & Immune Markers

Screens for hidden autoimmune activity or immune dysregulation.

  • ANA (Antinuclear Antibody) – Common screening test for autoimmune disorders.
  • Rheumatoid Factor (RF IgM) – Used in the assessment of joint and systemic inflammation.

Toxic Metals & Environmental Exposure

Monitors heavy metal burden which may interfere with endocrine and neurological function.

  • Lead – Associated with cognitive dysfunction, hypertension, and kidney damage.
  • Mercury – Can impair detox pathways and affect neurological function.

🔹 Additional Biomarkers

  • Leptin – A hormone involved in appetite regulation and metabolic signaling.
  • ABO Group & Rh Type – Blood typing for transfusion, pregnancy planning, or immunologic considerations.
  • CBC (Complete Blood Count) – Baseline measure of blood health, oxygenation, and immune status.

Fasting Guidelines

  • Fasting recommended for 8–12 hours
  • Only water allowed; avoid supplements, alcohol, and vigorous exercise beforehand

✅ Ideal For:

  • Men with chronic, unexplained symptoms
  • Patients interested in longevity, performance, or bio-optimization
  • Individuals with family history of cardiovascular, autoimmune, or metabolic disease
  • Athletes, executives, and high performers seeking personalized health insights
  • Those pursuing root-cause analysis in a functional medicine setting

Clinical Applications

  • Guide customized nutrition, supplementation, and lifestyle protocols
  • Identify hormonal dysfunctions (low T, thyroid imbalances)
  • Assess inflammatory and cardiometabolic risk before disease onset
  • Monitor detox and nutrient sufficiency for prevention and recovery
  • Support care for men with fatigue, brain fog, mood changes, or low libido