Description
Understand your genetic risk for heart disease and cognitive decline.
Overview:
The Apolipoprotein E (ApoE) Genotyping Test analyzes your genetic variant of the ApoE gene to assess your inherited risk for cardiovascular disease and late-onset Alzheimer's disease. This test helps guide preventive strategies by identifying which version(s) of the ApoE gene you carry — E2, E3, or E4.
Why It Matters:
Different ApoE variants impact how your body processes cholesterol and inflammation, which play a role in both heart health and brain aging.
- Individuals with one or two copies of the E4 allele may have a significantly higher risk of developing Alzheimer’s and atherosclerosis.
- Those with the E2 variant may have a lower Alzheimer’s risk but could be predisposed to other lipid abnormalities.
What This Test Identifies:
- ApoE Genotype (E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, or E4/E4)
- Associated Risk Factors:
- E4: Higher risk for Alzheimer’s and heart disease
- E3: Neutral or average risk
- E2: Possibly protective for Alzheimer’s but linked to lipid disorders
Who Should Consider This Test:
- Individuals with a family history of Alzheimer’s disease or dementia
- Those with a personal or family history of high cholesterol or heart disease
- Patients interested in personalized prevention strategies
- Anyone looking to take a proactive approach to aging and brain health
Test Details:
- Sample Type: Blood
- Fasting Required: No
