Description

Beta-2 microglobulin (B2M) is a small protein that serves as an important marker for certain cancers and kidney function.

Why the B2M Test Is Important

  • Cancer Monitoring: Elevated B2M levels in the blood can indicate the presence or progression of blood cancers, such as multiple myeloma or lymphoma, and may reflect tumor burden or prognosis.
  • Kidney Health: B2M is filtered by the kidneys, so high levels in urine or blood can indicate kidney dysfunction or damage.

Function in the Immune System

  • B2M is a component of MHC Class I molecules on cell surfaces.
  • It helps the immune system present antigens to cytotoxic T cells, allowing the body to recognize and destroy infected or cancerous cells.

Fasting: Not required.