Description

The Breast Cancer Risk Blood Panel screens for mutations in the BRCA1 and BRCA2 genes, which significantly increase the risk of developing breast, ovarian, and other cancers. Understanding whether you carry these genetic mutations can help you make informed, proactive decisions regarding your health.

Why Test for BRCA1 and BRCA2?

BRCA1 and BRCA2 are tumor suppressor genes that help repair damaged DNA. When these genes are mutated, their ability to repair DNA is compromised, allowing damaged cells to develop into cancer more easily.

  • Risk Identification: Individuals with harmful BRCA mutations have a much higher lifetime risk of developing breast and/or ovarian cancer compared to those without the mutation.
  • Proactive Health Management: If a BRCA mutation is detected, you can take preventive measures such as:
  • Enhanced cancer screenings (e.g., earlier and more frequent mammograms, MRIs)
  • Preventive medications
  • Risk-reducing surgeries (e.g., prophylactic mastectomy or oophorectomy)
  • Testing for family members

Who Should Consider This Test?

This test is recommended for individuals who:

  • Have a personal or family history of breast, ovarian, fallopian tube, or peritoneal cancer
  • Were diagnosed with breast cancer at an early age (under 50)
  • Have multiple family members with BRCA-related cancers
  • Have Ashkenazi Jewish ancestry, as this group carries a higher BRCA mutation rate

What This Test Involves

  • Blood Sample: A blood sample is drawn and analyzed for specific mutations in the BRCA1 and BRCA2 genes.
  • Results Interpretation: Results are reviewed by a genetic specialist to assess your level of cancer risk.

Important to Know

  • A positive result means you are at a higher risk of developing cancer, but it does not mean you currently have cancer.
  • A negative result means no known harmful mutations were detected, but it doesn’t eliminate all cancer risks.
  • Genetic counseling is recommended both before and after the test to help you fully understand your results and what actions may be needed.

Fasting Requirement

Fasting is not required for this test.

This Breast Cancer Risk Blood Panel offers valuable information to help you take charge of your health by understanding your genetic risk for breast cancer. It empowers you to make informed decisions about preventive health measures, monitoring, and family health planning.