Description
Chronic Kidney Disease (CKD) is a progressive condition in which the kidneys lose their ability to effectively filter waste, excess fluids, and toxins from the blood. Early detection and regular monitoring of specific biomarkers are critical to slowing disease progression, managing complications, and improving quality of life.
Common Causes of CKD:
- Diabetes
- High blood pressure
- Heart disease
- Family history of kidney disease
- Obesity
- Long-term use of certain medications (e.g., NSAIDs, some antibiotics)
Symptoms of CKD:
- Fatigue
- Swelling in the feet, ankles, or legs
- Shortness of breath
- Loss of appetite
- Nausea
- Muscle cramps
- Frequent urination, especially at night
Key Biomarkers Included in This Panel:
- Complete Blood Count (CBC)
- Evaluates overall blood health. Key markers like hemoglobin and hematocrit help detect anemia, which is common in advanced stages of CKD.
- Comprehensive Metabolic Panel (CMP)
- Provides critical information on kidney and liver function, electrolyte levels, and blood glucose—all important for identifying metabolic imbalances associated with CKD.
- Ferritin
- Reflects iron storage levels. Low ferritin may indicate iron-deficiency anemia, a frequent complication of CKD.
- Intact Parathyroid Hormone (PTH)
- Measures levels of PTH, which plays a central role in regulating calcium and phosphorus metabolism. CKD often leads to secondary hyperparathyroidism, indicated by elevated PTH levels.
- Phosphorus
- As kidney function declines, phosphorus levels often rise, which can contribute to bone demineralization and cardiovascular issues.
Fasting Requirement:
Not required
Why This Panel Is Important:
This panel helps detect CKD early, track disease progression, and monitor complications such as anemia, electrolyte imbalances, and bone-mineral disorders. By regularly measuring these biomarkers, healthcare providers can tailor treatment plans to support kidney health and manage symptoms more effectively.
