Description

Cytomegalovirus (CMV) is a common virus that belongs to the herpesvirus family. Although most people infected with CMV experience mild or no symptoms, the virus can cause serious health problems in newborns and individuals with weakened immune systems. This blood test measures CMV-specific IgG and IgM antibodies, helping determine if you have a current, past, or reactivated infection.

Why This Test Matters:

  • IgM antibodies are the body’s initial immune response to a new CMV infection or viral reactivation.
  • IgG antibodies appear later and typically remain in the body for life, providing long-term immunity.
  • Detecting both types of antibodies helps differentiate between a recent or current infection, a past infection, or viral reactivation.

Who Should Get Tested:

You may consider this test if you:

  • Are experiencing symptoms associated with CMV.
  • Are pregnant or planning pregnancy.
  • Have a weakened immune system (e.g., HIV/AIDS, organ transplant, cancer treatment).
  • Are a newborn or child showing developmental or neurological concerns.
  • Are a blood or organ donor/recipient.
  • Need CMV screening for medical clearance or pre-surgical evaluation.

Common Symptoms of CMV Infection:

  • Fatigue or weakness
  • Swollen lymph nodes
  • Sore throat
  • Fever or headache
  • Muscle aches
  • Jaundice (yellowing of the skin/eyes)
  • Low platelet count
  • Enlarged spleen or liver
  • Vision or hearing problems
  • Pneumonia
  • Seizures or delayed development (in infants)

What This Panel Includes:

CMV IgM Antibodies

  • Indicates: Recent infection or reactivation.
  • Detectable: Within 1–2 weeks of exposure.
  • Useful for: Diagnosing acute illness or tracking viral activity in immunocompromised individuals.

CMV IgG Antibodies

  • Indicates: Past exposure or immunity.
  • Detectable: Several weeks after infection.
  • Useful for: Determining long-term immunity, prenatal screening, and transplant compatibility.

Test Preparation:

  • Fasting: Not required
  • Special Instructions: Avoid taking biotin supplements (vitamin B7) at least 24 hours before testing, as it may interfere with results.
  • Sample Type: Blood (venipuncture)

Why Early Detection is Important:

CMV may go unnoticed in healthy individuals, but in pregnancy or immunosuppressed conditions, undetected CMV can have serious complications, including:

  • Birth defects
  • Developmental delays
  • Neurological damage
  • Severe systemic illness

Testing can guide treatment decisions, help prevent transmission, and allow for closer monitoring when needed.

Take Control of Your Health:

Whether you're experiencing symptoms, planning a pregnancy, or need to confirm immunity, the CMV IgG & IgM Antibody Panel provides valuable insight into your immune response and viral status.