Description
The HS-CRP blood test measures the level of C-reactive protein (CRP) in the blood, a protein produced by the liver in response to inflammation. High-sensitivity CRP testing can detect low levels of inflammation, which may indicate an increased risk of cardiovascular disease.
Purpose of the Test
- Assess chronic low-grade inflammation in the body
- Evaluate risk of heart attack, stroke, or other cardiovascular events
- Monitor effectiveness of treatments for conditions associated with inflammation (e.g., statin therapy)
- Track inflammatory conditions such as rheumatoid arthritis or lupus
How the Test Works
- A blood sample is drawn and analyzed using a high-sensitivity assay that can detect CRP levels lower than those identified by standard CRP tests
- Results are reported in milligrams per liter (mg/L)
When to Order
Individuals may order an HS-CRP test if they:
- Have risk factors for cardiovascular disease (high cholesterol, diabetes, hypertension, smoking, family history)
- Are being monitored for chronic inflammatory conditions
- Want to assess overall inflammatory status to guide lifestyle or treatment decisions
Interpretation of Levels
- Low risk: <1 mg/L
- Average risk: 1–3 mg/L
- High risk: >3 mg/L
Note: HS-CRP is a general marker of inflammation and does not indicate the exact source. Other tests may be needed to identify the cause of elevated levels.
Fasting not required.