Description

The HS-CRP blood test measures the level of C-reactive protein (CRP) in the blood, a protein produced by the liver in response to inflammation. High-sensitivity CRP testing can detect low levels of inflammation, which may indicate an increased risk of cardiovascular disease.

Purpose of the Test

  • Assess chronic low-grade inflammation in the body
  • Evaluate risk of heart attack, stroke, or other cardiovascular events
  • Monitor effectiveness of treatments for conditions associated with inflammation (e.g., statin therapy)
  • Track inflammatory conditions such as rheumatoid arthritis or lupus

How the Test Works

  • A blood sample is drawn and analyzed using a high-sensitivity assay that can detect CRP levels lower than those identified by standard CRP tests
  • Results are reported in milligrams per liter (mg/L)

When to Order

Individuals may order an HS-CRP test if they:

  • Have risk factors for cardiovascular disease (high cholesterol, diabetes, hypertension, smoking, family history)
  • Are being monitored for chronic inflammatory conditions
  • Want to assess overall inflammatory status to guide lifestyle or treatment decisions

Interpretation of Levels

  • Low risk: <1 mg/L
  • Average risk: 1–3 mg/L
  • High risk: >3 mg/L

Note: HS-CRP is a general marker of inflammation and does not indicate the exact source. Other tests may be needed to identify the cause of elevated levels.

Fasting not required.