Description

Identify Toxic Burdens. Support Targeted Detoxification.

The Environmental Pollutants Profile (EPP) is a specialized laboratory test that quantitatively measures 14 urinary metabolites associated with exposure to common environmental toxins. These include compounds from industrial solvents, plastics (phthalates), petroleum byproducts, and preservatives—many of which are pervasive in modern living.

By analyzing these metabolites, the EPP helps clinicians assess an individual’s toxic load and develop personalized detoxification and nutritional strategies to support long-term health.

What the Test Measures

The following biomarkers are evaluated to reflect exposure to petrochemicals, phthalates, benzenes, and other volatile organic compounds (VOCs):

Aromatic Hydrocarbon Metabolites

Associated with exposure to petroleum products, solvents, and plastics:

  • Hippuric Acid
  • Benzoic Acid
  • 4-Hydroxybenzoic Acid
  • Mandelic Acid
  • Phenylglyoxylic Acid
  • Mandelate + Phenylglyoxylate
  • t,t-Muconic Acid

Phthalate Metabolites

Indicators of plasticizer exposure (commonly found in food packaging, personal care products, and household items):

  • Monoethyl Phthalate (MEP)
  • Phthalates (composite marker)

Xylene & Toluene Exposure

Metabolites associated with industrial solvents and gasoline:

  • 2-Methylhippuric Acid
  • 3-Methylhippuric Acid
  • 3,4-Dimethylhippurate

Other Key Metabolites

  • 2-Hydroxyisobutyric Acid – linked to gasoline additives and synthetic solvents
  • Quinolinic Acid – a neurotoxic metabolite, often elevated with oxidative stress and toxic burden

Why Test for Environmental Pollutants?

Chronic low-level exposure to environmental toxins is increasingly recognized as a contributing factor to many health conditions, including:

  • Hormonal imbalances
  • Neurological symptoms
  • Fatigue and brain fog
  • Immune dysregulation
  • Cancer risk
  • Detoxification challenges

Understanding your body’s toxic load allows for informed intervention using nutrition, lifestyle changes, and personalized detox protocols.

Clinical Benefits

The EPP provides:

  • Quantitative insights into environmental toxin exposure
  • A foundation for targeted detoxification support
  • Evidence-based guidance for lifestyle and environmental modifications
  • Monitoring of patient response to detox therapies

Who Should Consider This Test?

  • Individuals with chemical sensitivities or chronic fatigue
  • Those living in urban or industrial environments
  • Patients with unexplained health issues or detox challenges
  • Anyone interested in preventive health and longevity

Preparation & Timing

  • Avoid collecting samples when:
  • You are menstruating.
  • You have a urinary tract infection.
  • If you take any medications and supplements, consult your healthcare provider regarding collection timing.
  • Some supplements and medications may impact results.
  • Do not discontinue prescription medications without consulting your healthcare provider.
  • Avoid the following preservatives for 48 hours before sample collection.
  • Sorbic acid/Sorbate
  • Benzoic acid/Sodium benzoate
  • Avoid excessive fluid intake the evening before collection.
  • If your sample is too dilute, it will not be able to be analyzed.