Description
The HSV-1 and HSV-2 IgG blood test measures type-specific antibodies in the blood to determine whether a person has been exposed to Herpes Simplex Virus type 1 (HSV-1) or type 2 (HSV-2). This test does not detect active outbreaks but identifies past infection and immunity status.
Purpose of the Test
- Detect previous exposure to HSV-1 or HSV-2
- Determine whether recurrent or unexplained symptoms are likely caused by HSV
- Support clinical decisions for management and prevention strategies
- Provide peace of mind for sexual partners regarding HSV status
How the Test Works
- Blood is drawn and analyzed for IgG antibodies, which the body produces weeks after initial infection and usually remain for life
- Type-specific assays differentiate HSV-1 (commonly oral herpes) from HSV-2 (commonly genital herpes)
- The presence of antibodies indicates past infection, not necessarily current active disease
When to Order
Individuals may order this test if they:
- Have a history of unexplained blisters or sores
- Are planning sexual activity with a new partner and want to know HSV status
- Are pregnant or planning pregnancy, to assess risk of neonatal herpes
- Have a partner diagnosed with HSV
Key Points
- A positive result indicates prior infection with HSV-1 or HSV-2
- A negative result means no detectable antibodies; however, early infections may not be detectable immediately
- This test does not detect active lesions—PCR or viral culture is required for current outbreaks
Fasting not required.
