Description
The RPR (Rapid Plasma Reagin) With Reflex to Titer blood test is a two-step process used to detect antibodies associated with syphilis, a sexually transmitted infection caused by Treponema pallidum.
- RPR Screening: Identifies the presence of antibodies that may indicate syphilis infection.
- Reflex to Titer: If the RPR is positive, the lab automatically measures antibody levels to determine disease activity and guide treatment decisions.
This testing approach provides both initial screening and quantitative follow-up in one convenient test.
Purpose of the Test
- Detect syphilis infection (primary, secondary, or latent stages)
- Quantify antibody levels to monitor treatment effectiveness
- Guide follow-up care for positive RPR results
- Aid in prevention of transmission to sexual partners
- Support prenatal screening to protect maternal and fetal health
Who Should Consider This Test?
- Individuals with risk factors for sexually transmitted infections
- Patients with symptoms of syphilis (sores, rash, fever, fatigue)
- Pregnant individuals as part of prenatal screening
- People undergoing STI testing for peace of mind
- Healthcare providers monitoring treatment response in confirmed syphilis cases
What the Test Measures
- RPR (Rapid Plasma Reagin): Detects nonspecific antibodies produced in response to syphilis infection.
- Titer (if reflexed): Measures the concentration of antibodies, helping determine disease stage and response to therapy.
A negative result generally rules out syphilis, while a positive result is followed by a titer to assess activity and guide treatment.
Fasting Required?
No fasting required.
