Description

Lipoprotein (a) (Lp(a)) testing is done to assess an individual's risk for cardiovascular disease, particularly heart disease, stroke, and other blood vessel diseases. Elevated Lp(a) levels are linked to a higher likelihood of these conditions. While it's not a routine screening test, it's often ordered for individuals at high risk due to family history, existing cardiovascular conditions, or other factors. 

Here's why a lipoprotein (a) test might be ordered:

  • Family history of early heart or blood vessel disease:
  • A family history of heart problems before age 55 (father or brother) or 65 (mother or sister) can increase the likelihood of Lp(a) testing. 

  • High LDL cholesterol:
  • Even if an individual is taking medication to lower LDL cholesterol, high Lp(a) levels can still contribute to cardiovascular risk. 

  • Existing heart or blood vessel disease:
  • If someone has heart or blood vessel disease, especially if cholesterol and triglyceride levels are normal, an Lp(a) test may be helpful. 

  • Signs of familial hypercholesterolemia:
  • This inherited condition causes high cholesterol levels, and Lp(a) testing might be considered. 

  • History of multiple heart attacks or angioplasties:
  • If someone has had multiple heart attacks or angioplasty procedures, an Lp(a) test might be ordered. 

  • Other cardiovascular risk factors:
  • Doctors may consider Lp(a) testing in individuals with other risk factors like diabetes, hypertension, or smoking. 

  • To assess the risk of cardiovascular events despite optimal LDL-lowering therapy:
  • Lp(a) is associated with recurrent cardiovascular events even when LDL cholesterol levels are managed effectively. 

Fasting not required.