Description
The Lupus Anticoagulant Screen is a blood test used to detect antibodies that interfere with the body’s normal clotting process. Despite the name, lupus anticoagulants are associated with an increased risk of abnormal blood clotting rather than bleeding.
This test is part of the antiphospholipid antibody evaluation and is commonly used to assess autoimmune-related clotting risk.
Why is this test important?
Lupus anticoagulants are associated with an increased risk of:
- Deep vein thrombosis (DVT)
- Pulmonary embolism
- Stroke or transient ischemic attack (TIA)
- Recurrent pregnancy loss
- Antiphospholipid syndrome (APS)
- Autoimmune diseases such as lupus
These antibodies may be present even when routine clotting tests are normal.
Who should consider this test?
This test may be helpful for individuals who have:
- Unexplained blood clots
- Recurrent miscarriages
- Early stroke without a clear cause
- Autoimmune disease or lupus
- Persistent inflammation with normal routine labs
- Family history of clotting disorders
- Evaluation for antiphospholipid syndrome
How is this test used?
The lupus anticoagulant screen is commonly used in:
- Antiphospholipid antibody panels
- Autoimmune evaluations
- Recurrent pregnancy loss workups
- Unexplained clotting investigations
- Advanced inflammation and immune assessments
It is often ordered alongside anticardiolipin and beta-2 glycoprotein antibodies for a more complete assessment.
Do I need to fast for this test?
Fasting is not required for the lupus anticoagulant screen.
