Description

Osteoporosis is a common bone disease in which bones become weak, brittle, and more prone to fractures. Often referred to as a “silent disease,” osteoporosis typically has no symptoms until a bone break occurs—often in the hip, spine, or wrist. While a bone density scan (DEXA) is the gold standard for diagnosis, blood testing helps identify underlying causes and contributing factors for low bone density.

Common Causes of Osteoporosis:

  • Hormonal changes (especially postmenopausal estrogen decline)
  • Nutrient deficiencies (like calcium and vitamin D)
  • Sedentary lifestyle
  • Smoking or heavy alcohol use
  • Medical conditions (e.g., thyroid, parathyroid, or kidney disorders)
  • Certain medications (e.g., steroids, anticonvulsants)

Symptoms May Include:

  • Bone fractures from minor injuries or falls
  • Back pain, especially if caused by spinal fractures
  • Loss of height over time
  • Stooped posture (kyphosis)

This Panel Includes the Following Biomarkers:

C-Peptide

  • Purpose: Evaluates insulin production.
  • Why it matters: Imbalances in insulin can reflect metabolic health, which is linked to bone density. Lower insulin levels can be associated with bone loss in certain populations.

Complete Blood Count (CBC)

  • Purpose: Assesses red and white blood cells, hemoglobin, and platelets.
  • Why it matters: Screens for anemia or chronic illness that may impact bone health or overall resilience.

Comprehensive Metabolic Panel (CMP)

  • Purpose: Provides a broad view of liver and kidney function, electrolytes, and glucose.
  • Why it matters: Kidney function and mineral balance are essential for maintaining strong bones.

Parathyroid Hormone (PTH) and Calcium

  • Purpose: Evaluates calcium regulation and parathyroid gland function.
  • Why it matters: Elevated PTH can lead to bone resorption, where calcium is pulled from the bones, weakening them. Calcium levels also indicate whether your body has enough of this key mineral to support bone formation.

Test Preparation:

  • Fasting: Not required
  • Sample Type: Blood (venipuncture)

Recommended For Individuals Who:

  • Have experienced a bone fracture
  • Are postmenopausal or have a family history of osteoporosis
  • Have symptoms of back pain or loss of height
  • Take medications that may impact bone density
  • Want to assess risk factors before or alongside a bone density scan

Why This Panel Matters:

This blood panel helps identify systemic imbalances that may contribute to osteoporosis. Understanding whether hormonal, metabolic, or nutritional issues are affecting bone strength allows for more personalized prevention and treatment strategies.