Description

PRO Gut Health Test — The Most Comprehensive Gut Microbiome and Stool Health Assessment

Nationwide Shipping Available – At-Home Collection Kit

Overview

The PRO Gut Health Test offers the most complete evaluation of gut health available today, combining shotgun metagenomics with non-microbial stool biomarkers to assess both the microbial ecosystem and physiological function of the gastrointestinal tract. This dual approach provides advanced insights into inflammation, digestion, immune activity, microbial balance, and gut barrier integrity.

This test cannot be ordered for individuals under 3 years old.

Why This Test Matters

This is the gold standard for anyone seeking a full-spectrum understanding of their gut health—whether for chronic digestive symptoms, autoimmune conditions, poor immunity, or simply optimizing wellness.

It’s ideal for individuals experiencing:

  • Bloating, gas, or irregular bowel movements
  • Food sensitivities or malabsorption
  • Chronic inflammation or autoimmune issues
  • Skin conditions, fatigue, or mood imbalances
  • Weight fluctuations or metabolic dysfunction
  • History of antibiotic or medication use
  • Concerns about gut barrier function or "leaky gut"

What the Report Includes

  • Strain-Level Resolution of gut microbiota
  • Relative Abundances of microbes
  • Microbial Function Analysis (vitamin synthesis, SCFA production, fermentation)
  • Non-Microbial Biomarkers related to inflammation, immune activity, and digestive enzyme function
  • Custom Insights & Actionable Data for diet, supplementation, and lifestyle
  • Personalized Recommendations for improving gut health

Sample Type & Processing

  • Sample Type: Stool (easy at-home collection kit)
  • Shipping: Nationwide, includes pre-paid return shipping
  • Shipping Time: 5–8 business days
  • Processing Time: Approx. 28 business days from lab receipt
  • Preparation: No fasting or diet change required

Key Biomarkers

Microbial Diversity & Abundance

  • Abundance Index, Richness Index, Shannon Diversity Index
  • Gut Type, F/B Ratio, P/B Ratio, Proteobacteria/Actinobacteria Ratio

Beneficial Microbes

  • Akkermansia spp., Bifidobacterium spp., Faecalibacterium spp., Roseburia spp., Blautia spp., Ruminococcus spp., Lacticaseibacillus spp., Phocaeicola dorei

Pathogens & Opportunists

  • Clostridium difficile, Candida spp., Aspergillus spp., Blastocystis spp., Cryptosporidium spp., Giardia, Salmonella enterica, Vibrio cholerae, Klebsiella spp., Campylobacter spp., H. pylori, Staphylococcus spp., Streptococcus spp., Enterococcus spp., E. coli, Yersinia enterocolitica, Saprochaete, Entamoeba histolytica

Digestive Function & Inflammation

  • Pancreatic Elastase 1 – Enzyme output from the pancreas
  • Calprotectin, Lactoferrin, Lysozyme – Inflammatory markers
  • Total Fecal Fat – Fat malabsorption indicator
  • Occult Blood – Hidden GI bleeding
  • SIgA – Secretory IgA for gut immune defense
  • Beta-Glucuronidase – Detoxification pathway
  • pH – Stool acidity

Metabolites & Functional Markers

  • SCFA Profile: Butyrate, Acetate, Propionate, Valerate (% and total)
  • Hydrogen Sulfide Index, Hexa-LPS Index, Mucus Degradation Index, Protein Breakdown
  • Histamine Producers – Inflammatory triggers

Prebiotic Utilization & Dietary Fiber Breakdown

  • Cellulose, Chitin, Pectin, Resistant Starch
  • Fructooligosaccharides, Galactooligosaccharides, Xylooligosaccharides, Isomaltooligosaccharides

Vitamin Production Potential

  • Microbial synthesis of Vitamins:
  • B2 (Riboflavin)
  • B7 (Biotin)
  • B9 (Folate)
  • B12 (Cobalamin)
  • K2 (Menaquinone)

Who Should Get This Test?

This test is perfect for:

  • Adults or children over 3 with chronic digestive symptoms (IBS, IBD, constipation, diarrhea, bloating)
  • Individuals with autoimmune or inflammatory conditions (rheumatoid arthritis, eczema, psoriasis)
  • Anyone seeking to optimize immunity, gut health, and nutritional absorption
  • People with mood disorders, fatigue, or brain fog linked to the gut-brain axis
  • Athletes and high-performance individuals focused on recovery, absorption, and gut resilience
  • People recovering from long-term medication use, especially antibiotics or NSAIDs
  • Functional and integrative medicine patients wanting deep insight for targeted intervention