Description

A Prostate Specific Antigen (PSA), Free and Total test is used to assess the risk of prostate cancer by measuring the level of PSA in a man's blood, specifically looking at the ratio of "free" PSA (unbound to other proteins) to total PSA (both free and bound), which can help differentiate between a benign condition like an enlarged prostate and potentially cancerous prostate tissue; a lower percentage of free PSA may indicate a higher likelihood of prostate cancer. 

Key points about the PSA, Free and Total test:

What it measures:

  • This test measures the amount of PSA protein in the blood, which is produced by the prostate gland. 

Why it's important:

  • While a high total PSA level can be a sign of prostate cancer, it can also be elevated due to other benign conditions like benign prostatic hyperplasia (BPH). By also measuring the "free" PSA, doctors can get a better idea of the likelihood that an elevated PSA is due to cancer. 

Interpretation of results:

  • High total PSA with a low percentage of free PSA: May suggest a higher risk of prostate cancer. 
  • High total PSA with a high percentage of free PSA: May indicate a benign condition like BPH.

Fasting not required.