Description

Thyroglobulin antibodies (TgAb) are proteins produced by the immune system that attack thyroglobulin, a protein found in the thyroid gland. The thyroid uses thyroglobulin to produce hormones that control metabolism and growth. 

TgAb levels can increase in people with thyroid-related autoimmune conditions, such as Hashimoto's thyroiditis or Graves' disease. TgAb levels can also be elevated in people with other autoimmune disorders, like rheumatoid arthritis, Celiac disease, and type 1 diabetes. 

Symptoms of high thyroglobulin antibodies include:

  • Anxiety or nervousness
  • Trouble sleeping
  • Chronic fatigue
  • Sensitivity to heat or cold
  • Forgetfulness
  • Poor concentration
  • Weight gain or weight loss
  • Muscle weakness or tremors

Fasting not required.