Description
The TgAb test detects thyroglobulin antibodies—proteins made by the immune system that mistakenly attack thyroglobulin, a key protein in your thyroid gland. Thyroglobulin is essential for producing hormones that regulate metabolism, energy, and growth.
Why It's Important:
- Helps diagnose autoimmune thyroid diseases such as Hashimoto’s thyroiditis and Graves’ disease
- May also be elevated in people with other autoimmune conditions like rheumatoid arthritis, Celiac disease, or type 1 diabetes
- Supports early detection and management of thyroid dysfunction before hormone levels become abnormal
Common Symptoms of Elevated TgAb:
- Anxiety or nervousness
- Fatigue or sleep issues
- Sensitivity to heat or cold
- Memory problems or brain fog
- Unexplained weight gain or loss
- Muscle weakness or tremors
Fasting not required.
This test can provide important insight into autoimmune activity and early thyroid disease—even before other labs show changes.

