Description

A vitamin D 1,25 hydroxy blood test, also known as a 1,25-dihydroxyvitamin D (DHVD) test, is used to diagnose disorders that affect calcium metabolism. It can also help assess vitamin D status in people with certain conditions, such as kidney disease or hypercalcemia. 

Why it's done

  • To diagnose disorders that affect calcium metabolism 
  • To assess vitamin D status in people with certain conditions, such as kidney disease or hypercalcemia 

When it's done

  • A health care provider may order this test if they suspect a bone or other health condition could be caused by low vitamin D levels 
  • It may be needed to diagnose disorders that affect calcium metabolism 

What it shows

  • Elevated levels of 1,25(OH)2D can be caused by extrarenal 1α-hydroxylation or hereditary vitamin D-resistant rickets 
  • Low levels of 25(OH)D can be caused by dietary deficiency, poor absorption, or impaired metabolism

Fasting not required.