Description

DNA Risk®: HLA-Related Autoimmunity Panel

Genetic Insights into Autoimmune Disease Risk

Autoimmune conditions are complex and often influenced by both genetic predispositions and environmental triggers. One of the strongest genetic contributors to autoimmune susceptibility lies in the Major Histocompatibility Complex (MHC)—specifically, Human Leukocyte Antigens (HLAs). These genes are central to immune system regulation, as they control how the body distinguishes between self and non-self.

The DNA Risk®: HLA-Related Autoimmunity Test offers in-depth insight into an individual’s genetic predisposition to a range of common autoimmune disorders, based on specific HLA allele variations and MHC-related markers.

Clinical Value

This test is ideal for:

  • Individuals diagnosed with autoimmune disorders seeking to understand their genetic background
  • Patients with a family history of autoimmune disease
  • Those exposed to environmental triggers (e.g., infections, gluten, heavy metals, or stress) who want to evaluate their risk
  • Clinicians seeking diagnostic support for patients with complex or undiagnosed immune-related symptoms

What the Report Provides

  • Detailed HLA Genotype Data presented in a user-friendly format
  • Disorder-specific risk profiles, including relevant environmental factors
  • Identification of both risk-enhancing and protective HLA alleles
  • Overview of immune-regulatory gene variants linked to susceptibility

Autoimmune Conditions Assessed

The report evaluates genetic associations with the following autoimmune disorders:

  • Alopecia Areata (AA)
  • Ankylosing Spondylitis (AS)
  • Celiac Disease (CD)
  • Graves’ Disease (GD)
  • Hashimoto’s Thyroiditis (HT)
  • IgA Nephropathy (IgAN)
  • Lyme Borreliosis (Chronic/Autoimmune response)
  • Multiple Sclerosis (MS)
  • Rheumatoid Arthritis (RA)
  • Systemic Lupus Erythematosus (SLE)
  • Vitiligo
  • Idiopathic Membranous Nephropathy (IMN)

This broad scope allows clinicians to better understand a patient’s immune system vulnerabilities and target preventive or therapeutic interventions accordingly.

Test Process & Timeline

  • Kit Order: Initiated when the test is purchased
  • Shipping Time: 2–5 business days to arrive at our facility
  • Sample Type: Buccal (cheek) swab for non-invasive DNA collection
  • Results: Delivered within approximately 25 business days from lab receipt

Understand Your Genetic Risk. Personalize Your Approach to Immune Health.

Early insight into autoimmune risk can empower both patients and providers to take proactive steps—whether through dietary changes, environmental adjustments, or targeted supplementation.

Order your DNA Risk® HLA-Related Autoimmunity Panel today and gain valuable clarity into your immune health blueprint.