Description
Anticardiolipin IgG is a blood test that detects autoimmune antibodies associated with abnormal clotting and immune system activation. It is part of the antiphospholipid antibody group and is commonly used to evaluate unexplained clotting risk and autoimmune conditions.
This marker helps identify immune-related clotting tendencies that are often not detected on routine lab testing.
Why is this test important?
Elevated anticardiolipin IgG antibodies may increase the risk of:
- Blood clots (DVT, pulmonary embolism, stroke)
- Antiphospholipid syndrome (APS)
- Recurrent pregnancy loss
- Autoimmune disorders such as lupus
- Post-viral inflammation, including Long COVID
Because these antibodies can be present even when routine labs are normal, this test offers deeper insight into hidden inflammatory and clotting risk.
Who should consider this test?
This test may be helpful for individuals who have:
- A personal or family history of blood clots
- Recurrent miscarriages
- Autoimmune symptoms or diagnosed autoimmune disease
- Persistent inflammation with normal routine labs
- Long COVID or post-viral symptoms
- Unexplained neurologic or vascular symptoms
How is this test used?
Anticardiolipin IgG is commonly included in advanced evaluations for:
- Autoimmune conditions
- Immune dysregulation and chronic inflammation
- Long COVID and post-viral syndromes
- Advanced cardiovascular risk screening
- Recurrent pregnancy loss workups
It is often ordered alongside other antiphospholipid antibodies for a more complete assessment.
Do I need to fast for this test?
Fasting is not required for anticardiolipin IgG testing. This test can be performed at any time of day and does not require special preparation.

