Description
Atrial fibrillation (AF) is a common heart rhythm disorder that increases the risk of stroke, heart failure, and other serious cardiovascular issues. Certain genetic variations can predispose individuals to develop AF. The 4q25 genetic variant is one such risk factor, linked to changes in the cardiac electrical signaling that contribute to the development of atrial fibrillation.
What Is the 4q25 Genetic Variant?
- The 4q25 locus is a specific region in the genome, and variations here are associated with an increased risk of atrial fibrillation.
- Individuals with this variant are at a higher risk for AF, even without other common risk factors like high blood pressure or heart disease.
Why Get Tested?
- Early identification of genetic predisposition can help with preventative measures and timely interventions, particularly for those with a family history or other cardiovascular risk factors.
- People at risk may benefit from more frequent heart monitoring or lifestyle changes to reduce their likelihood of AF.
How the Test Works
- The test involves a simple swab of the inside of the cheek (buccal swab) to collect genetic material.
- Test focuses solely on the 4q25 variant, which is the most commonly researched and identified genetic risk factor for AF.
Test Instructions
- Avoid the following for 30 minutes before sample collection:
- Eating
- Smoking
- Drinking caffeinated beverages (including coffee, tea, or energy drinks)
Results Timeline
- Allow 14 business days for test results, not including transportation time.
No Fasting Required
- You do not need to fast before taking the test.
By identifying the 4q25 risk variant, this test provides valuable information for individuals concerned about atrial fibrillation, helping them make informed decisions regarding their cardiovascular health.
