Description

Got it — here is the updated LabsByRequest.com style combined panel page with the additional tests included:

  • Factor V Leiden Mutation Analysis
  • Homocysteine
  • Thyroglobulin Antibody

Clean, consistent with your site format.

Advanced Clotting and Autoimmune Thrombosis Panel

What is this panel?

This comprehensive panel evaluates autoimmune, genetic, and functional causes of abnormal blood clotting. It combines antiphospholipid antibodies, inherited thrombophilia testing, natural anticoagulant activity, and additional inflammation markers to provide a broader assessment of clotting risk.

This type of testing is often used when evaluating unexplained clotting, recurrent pregnancy loss, stroke risk, or persistent inflammation despite normal routine labs.

What does this panel include?

Antiphospholipid Antibody Panel Evaluates autoimmune antibodies associated with antiphospholipid syndrome (APS) and autoimmune clotting risk.

Anticardiolipin IgG Measures a key autoimmune antibody linked to increased clot risk and APS.

Lupus Anticoagulant Screen (no confirmation) Screens for antibodies that interfere with clotting pathways and are associated with autoimmune thrombosis.

Protein C Activity Assesses a natural anticoagulant protein that helps regulate clot formation. Low activity may increase thrombosis risk.

Protein S Activity Works with Protein C to prevent excessive clotting. Reduced activity may contribute to inherited or acquired thrombophilia.

Antithrombin III Activity A key regulator of clotting enzymes. Low levels are associated with increased clot risk.

Factor V Leiden Mutation Analysis Genetic testing for one of the most common inherited clotting mutations. This mutation increases the risk of venous thrombosis and inherited thrombophilia.

Homocysteine Blood Test Measures homocysteine, an amino acid associated with vascular inflammation and increased risk of clotting and cardiovascular disease.

Thyroglobulin Antibody (TgAb) Evaluates autoimmune thyroid activity. Thyroid autoimmunity may contribute to inflammation, pregnancy complications, and immune-related clotting risk.

Why is this panel important?

Abnormal clotting risk can result from a combination of autoimmune antibodies, inherited mutations, inflammation, and metabolic factors. Standard lab testing often does not evaluate these pathways.

This panel helps assess risk for:

  • Deep vein thrombosis (DVT)
  • Pulmonary embolism
  • Stroke or transient ischemic attack (TIA)
  • Recurrent pregnancy loss
  • Antiphospholipid syndrome (APS)
  • Inherited thrombophilia
  • Autoimmune-related clotting
  • Vascular inflammation

Who should consider this panel?

This panel may be helpful for individuals who have:

  • Personal or family history of blood clots
  • Clotting at a young age
  • Recurrent miscarriages
  • Unexplained stroke or TIA
  • Autoimmune disease or suspected APS
  • Strong family history of thrombophilia
  • Elevated inflammation with normal routine labs
  • Long COVID or persistent inflammatory symptoms

How is this panel used?

This panel is commonly used in:

  • Advanced thrombophilia evaluations
  • Autoimmune clotting assessments
  • Recurrent pregnancy loss workups
  • Unexplained clotting investigations
  • Preventive cardiovascular screening
  • Pre-hormone therapy risk evaluation

It provides a broader view by assessing autoimmune, genetic, and functional clotting pathways.

Do I need to fast for this panel?

Fasting is not required for most tests in this panel.