Description

Non-Invasive Genetic Testing for Methylation and Neurotransmitter Function

This test detects variations (SNPs) in the COMT (Catechol-O-Methyltransferase) gene, which plays a crucial role in breaking down neurotransmitters like dopamine, epinephrine, and norepinephrine—as well as metabolizing estrogen and catechols involved in detoxification.

Understanding your COMT genotype can help personalize approaches to:

  • Mood and anxiety support
  • Estrogen metabolism
  • Stress response
  • Methylation balance
  • Supplementation with methyl donors (like methylfolate or SAMe)

Swab-Based Collection – No Blood Draw Required

This version of the COMT test uses a simple cheek swab for DNA collection—ideal for those seeking a non-invasive, at-home testing option.

Why It Matters:

  • Certain COMT variants can lead to slower or faster breakdown of neurotransmitters and estrogens
  • Can influence your response to methylated B vitamins, adaptogens, and detox protocols
  • Provides valuable insight for those with MTHFR, hormone imbalances, anxiety, or fatigue

Test Info:

  • Sample type: Buccal (cheek) swab
  • Fasting: Not required
  • Shipping: Nationwide availability