Description
The Estradiol (E2) Ultra-Sensitive Blood Test measures very low levels of estradiol, a key form of estrogen, in the blood. Estradiol is a hormone produced mainly by the ovaries in women and, in smaller amounts, by the adrenal glands and testes in men.
Purpose of the Test:
- To assess ovarian function and monitor fertility.
- To evaluate menopausal status and hormone replacement therapy.
- To monitor patients with hormone-sensitive cancers, such as breast or prostate cancer.
- To detect estrogen deficiency or excess.
Clinical Uses:
- Fertility Assessment: Helps determine ovarian reserve and timing of ovulation.
- Menopause & Perimenopause: Monitors declining estrogen levels to guide therapy.
- Hormone Therapy Monitoring: Ensures correct dosing for patients receiving estrogen therapy.
- Cancer Monitoring: Used in follow-up for hormone-sensitive cancers to detect recurrence or residual disease.
Preparation & Collection:
- Blood is drawn via venipuncture.
- Fasting is not required.
- For premenopausal women, timing may be coordinated with the menstrual cycle for accurate interpretation.
Clinical Interpretation:
- Low Estradiol: May indicate menopause, ovarian failure, or hypothalamic-pituitary disorders.
- High Estradiol: May indicate ovarian tumors, estrogen therapy, or certain cancers.
- Fluctuating Levels: Can reflect normal cycle variations in premenopausal women.
