Description
Test kits available for nationwide shipping for patient convenience
The Organic Acids Test (OAT) provides a comprehensive metabolic snapshot of a patient’s overall health by analyzing organic acids in the urine. This test assesses intestinal yeast and bacterial overgrowth, vitamin and mineral levels, oxidative stress, neurotransmitter metabolites, and oxalate burden. It is a valuable tool for identifying underlying metabolic imbalances that may contribute to fatigue, digestive issues, neurological symptoms, and chronic health conditions.
Detailed Biomarker Insights: Organic Acids Test (OAT)
2-Hydroxybutyric Acid:
Elevated levels may indicate oxidative stress and impaired glutathione metabolism, often associated with insulin resistance or early diabetes.
2-Hydroxyhippuric Acid:
Marker linked to gut microbial metabolism and detoxification processes.
2-Hydroxyisocaproic Acid:
A leucine metabolite; abnormal levels may reflect metabolic dysfunction or nutrient deficiencies.
2-Hydroxyisovaleric Acid:
Associated with biotin deficiency and certain metabolic disorders.
2-Hydroxyphenylacetic Acid:
Indicator of gut bacteria metabolism; elevated in dysbiosis.
2-Oxo-4-methiolbutyric Acid:
Involved in methionine metabolism; may reflect methylation status.
2-Oxoglutaric Acid:
A key intermediate in the Krebs cycle; abnormal levels can indicate mitochondrial dysfunction.
2-Oxoisocaproic Acid & 2-Oxoisovaleric Acid:
Markers of amino acid metabolism, can signal metabolic imbalances.
3-Hydroxybutyric Acid:
A ketone body elevated during fasting or fat metabolism; abnormal levels may suggest metabolic stress.
3-Hydroxyglutaric Acid:
Associated with fatty acid metabolism and some metabolic diseases.
3-Indoleacetic Acid:
Product of tryptophan metabolism by gut bacteria; elevated levels suggest dysbiosis.
3-Methyl-2-oxovaleric Acid:
An intermediate in isoleucine metabolism; abnormal levels indicate metabolic issues.
3-Methylglutaconic Acid & 3-Methylglutaric Acid:
Markers of mitochondrial dysfunction and organic acidurias.
4-Cresol:
Produced by bacterial fermentation in the gut; elevated levels indicate dysbiosis and toxin buildup.
4-Hydroxybenzoic Acid:
A microbial metabolite with antioxidant properties; altered levels suggest gut microbial imbalance.
4-Hydroxybutyric Acid (GHB):
Abnormal levels may relate to neurological disorders or metabolic dysfunction.
4-Hydroxyphenylacetic Acid & 4-Hydroxyphenyllactic Acid:
Markers of phenylalanine and tyrosine metabolism; elevated in gut dysbiosis.
5-HIAA (5-Hydroxyindoleacetic Acid):
The main serotonin metabolite; helps assess serotonin turnover, linked to mood and GI function.
Acetoacetic Acid:
A ketone body reflecting fat metabolism; abnormal levels may indicate energy metabolism disturbances.
Adipic Acid:
Elevated in disorders of fatty acid metabolism or increased oxidative stress.
Arabinose:
A sugar metabolite indicating yeast or fungal overgrowth.
Ascorbic Acid (Vitamin C):
Reflects antioxidant status and nutritional sufficiency.
Citric Acid, Aconitic Acid, Malic Acid, Succinic Acid, Fumaric Acid:
Krebs cycle intermediates; imbalances can signal mitochondrial energy production issues.
DOPAC & HVA:
Dopamine metabolites indicating neurotransmitter turnover relevant to mood and cognitive health.
Ethylmalonic Acid:
Elevated levels may indicate short-chain fatty acid metabolism issues.
Furan-2,5-dicarboxylic Acid & Furancarbonylglycine:
Markers linked to environmental toxin exposure and gut microbial metabolism.
Glutaric Acid:
Elevated in organic acidemias; may reflect metabolic stress.
Glyceric Acid & Glycolic Acid:
Associated with carbohydrate and fatty acid metabolism.
Hippuric Acid:
A gut microbial metabolite; elevated levels may indicate increased toxin load or dysbiosis.
Homogentisic Acid:
Abnormal levels linked to rare metabolic diseases affecting connective tissue.
Kynurenic Acid & Quinolinic Acid:
Tryptophan metabolites involved in neuroinflammation and neurological health.
Lactic Acid:
Elevated with anaerobic metabolism and mitochondrial dysfunction.
Methylmalonic Acid (MMA):
A sensitive marker of vitamin B12 deficiency.
Mandelic Acid:
Elevated in cases of toxin exposure or infections.
N-Acetylaspartic Acid (NAA):
A neuronal marker; decreased levels can indicate neurodegeneration.
Orotic Acid:
High levels may suggest urea cycle disorders or pyrimidine metabolism issues.
Oxalic Acid:
High levels can contribute to kidney stone formation.
Pantothenic Acid (Vitamin B5):
Reflects nutritional status related to energy metabolism.
Phenyllactic Acid & Phenylpyruvic Acid:
Elevated in phenylketonuria (PKU) and metabolic dysfunction.
Pyridoxic Acid:
Vitamin B6 metabolite; low levels can impair many enzymatic functions.
Pyroglutamic Acid:
Related to glutathione metabolism and detoxification capacity.
Pyruvic Acid:
Central to glucose metabolism; abnormal levels indicate metabolic stress.
Sebacic Acid & Suberic Acid:
Dicarboxylic acids linked to fatty acid oxidation disorders.
Tartaric Acid:
A dietary acid; elevated levels may suggest fungal overgrowth.
Thymine & Uracil:
Pyrimidine bases; abnormalities can indicate DNA/RNA metabolism issues.
Vanillylmandelic Acid (VMA):
Catecholamine metabolite, important in assessing adrenal function and stress response.
Why Choose the Organic Acids Test?
- Comprehensive insight into metabolic health and nutrient status
- Detects markers of gut dysbiosis, yeast overgrowth, and bacterial imbalances
- Identifies oxidative stress and detoxification inefficiencies
- Measures neurotransmitter metabolites that affect mood and cognition
- Evaluates oxalate levels related to kidney and joint health
Sample Collection
- Sample Type: Urine collection
- Fasting: Typically fasting is not required; follow provider instructions
- Shipping: Test kits available for nationwide shipping for patient convenience
