Description

Track your hormone rhythm across a full cycle—naturally.

The Rhythm Plus™ test is a comprehensive 28-day salivary hormone panel designed specifically for premenopausal and perimenopausal women who are not currently using hormone therapy. Unlike one-time blood tests, this advanced panel captures your hormone fluctuations throughout your entire cycle, giving you and your provider a more accurate picture of what’s really happening with your hormones day-to-day.

This test combines sex hormone tracking, adrenal function, and melatonin analysis—making it one of the most complete non-invasive assessments of hormonal health available.

Why Choose Rhythm Plus™?

Hormone levels vary not just by day—but hour, mood, stress, sleep, and age. A single snapshot doesn’t always tell the full story.

This test is ideal for women experiencing:

  • Irregular menstrual cycles
  • Mood swings or irritability
  • PMS or PMDD
  • Sleep disturbances
  • Mid-cycle spotting
  • Fertility concerns
  • Perimenopausal symptoms (even if still cycling)
  • Fatigue, anxiety, or low libido without clear answers from standard tests

What This Test Measures

This panel includes 6 key salivary biomarkers, collected multiple times over a 28-day cycle to track hormonal patterns, identify imbalances, and assess overall rhythm:

Cortisol

The body’s primary stress hormone. Rhythm Plus™ measures your daily cortisol curve to assess adrenal function and stress response.

DHEA

A precursor to both estrogen and testosterone. Helps evaluate adrenal health and hormonal aging.

Estradiol (E2)

The primary form of estrogen. Fluctuations are tracked across your cycle to detect estrogen dominance, deficiency, or irregular ovulation.

Progesterone

Critical for regulating the second half of the cycle. Low levels or poor rhythm can contribute to PMS, infertility, and perimenopausal symptoms.

Testosterone

Supports libido, motivation, and energy. Levels are evaluated for both deficiency and androgen excess.

Melatonin

Your body’s sleep-wake hormone. Assessed through the Comprehensive Melatonin Profile to uncover circadian disruption, insomnia, or low overnight output.

How the Test Works

  • Collection Method: Saliva samples, collected at home over 28 days
  • Non-invasive: No blood draw, no needles
  • Shipping: Nationwide kit delivery and return shipping included
  • Best For: Cycling women not currently on hormone replacement therapy

Fasting: Not required

Test Duration: 28 days

Specimen Type: Saliva

Availability: Nationwide shipping included