Description
The Sex Hormone Binding Globulin (SHBG) Blood Test measures the level of SHBG, a protein produced by the liver that binds to sex hormones like testosterone and estradiol. SHBG regulates the availability of these hormones to tissues, influencing reproductive, metabolic, and sexual health.
This test provides valuable insight into hormone balance and can help diagnose or monitor conditions related to low or high sex hormone activity.
Purpose of the Test
- Evaluate hormone availability and balance in men and women
- Assess risk factors for metabolic syndrome or insulin resistance
- Support diagnosis of thyroid disorders, liver disease, or polycystic ovary syndrome (PCOS)
- Investigate causes of low libido, fatigue, or menstrual irregularities
- Monitor testosterone or estrogen therapy effectiveness
Who Should Consider This Test?
- Men with low testosterone symptoms (fatigue, low libido, muscle weakness)
- Women with irregular menstrual cycles, infertility, or PCOS
- Individuals with thyroid, liver, or metabolic disorders
- Patients on hormone replacement therapy seeking monitoring
- People concerned about hormone-driven conditions affecting sexual or metabolic health
What the Test Measures
- SHBG Levels: Determines the amount of sex hormones bound and unbound in the bloodstream.
- Free vs. Bound Hormones: SHBG helps calculate free testosterone and free estradiol, which are biologically active and available to tissues.
High SHBG levels can reduce the availability of testosterone and estradiol, potentially causing symptoms like fatigue, low libido, or menstrual irregularities.
Low SHBG levels may increase free hormones, which can be linked to conditions like PCOS, insulin resistance, or metabolic syndrome.
Fasting Required?
No fasting required.
